Dictionary Meaning and Definition on 'Substrates'
Wikipedia Meaning and Definition on 'Substrates'
In biochemistry, a substrate is a molecule upon which an enzyme acts. Enzymes catalyze chemical reactions involving the substrate(s). In the case of a single substrate, the substrate binds with the enzyme active site, and an enzyme-substrate complex is formed. The substrate is transformed into one or more products, which are then released from the active site. The active site is now free to accept another substrate molecule. In in the case of more than one substrate, these may bind in a particular order to the active site, before reacting together to produce products.
For example, curd formation (rennet coagulation) is a reaction that occurs upon adding the enzyme rennin to milk. In this reaction, the substrate is a milk protein (e.g., casein) and the enzyme is rennin. The products are two polypeptides that have been formed by the cleavage of the larger peptide substrate. Another example is the chemical decomposition of hydrogen peroxide carried out by the enzyme catalase. As enzymes are catalysts, they are not changed by the reactions they carry out. The substrate(s), however, is/are converted to product(s). Here, hydrogen peroxide is converted to water and oxygen gas.[See more about Substrates at Dictionary 3.0 Encyclopedia]
Words and phrases related to 'Substrates'
Substrates Sample Sentences in News
- Research and Markets: Free-Standing & Bulk GaN Substrates for Laser Diode, LED and Power Electronics Report
Research and Markets has announced the addition of the "Free-Standing & Bulk GaN Substrates for Laser Diode Read more on this news related to 'Substrates'
- NCI Grant Targets a Key Enzyme in Cancer
Immunologists on a multi-institution research team will share a five-year, $4.8 million National Cancer Institute grant to target multiple diseases including cancer, Alzheimer's and graft-versus-host disease by manipulating an enzyme that activates over 100 different protein substrates in the body. Read more on this news related to 'Substrates'
- Novel bio-inspired method to grow high-quality graphene for high-end electronic devices
Researchers have successfully developed an innovative one-step method to grow and transfer high-quality graphene on silicon and other stiff substrates, opening up opportunities for graphene to be used in high-value applications that are currently not technologically feasible. Read more on this news related to 'Substrates'