Cortisone

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Dictionary Meaning and Definition on 'Cortisone'

Cortisone Meaning and Definition from WordNet (r) 2.0
    cortisone n : a corticosteroid hormone (trade name Cortone Acetate) normally produced by the adrenal cortex; is converted to hydrocortisone [syn: Cortone Acetate]
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Wikipedia Meaning and Definition on 'Cortisone'


220–224 °C

Cortisone (pronounced /ˈkɔrtɨsoʊn/ or /ˈkɔrtɨzoʊn/ (ˈkôrtəˌsōn or -zōn)) (17-hydroxy-11-dehydrocorticosterone) is a steroid hormone. In chemical structure, it is a corticosteroid closely related to corticosterone. It is used to treat a variety of ailments and can be administered intravenously, orally, intraarticularly, or cutaneously. Cortisone suppresses the immune system, thus reducing inflammation and attendant pain and swelling at the site of the injury. Risks exist, in particular in the long-term use of cortisone.

Cortisone was first identified by the American chemist Edward Calvin Kendall while a researcher at the Mayo Clinic. He was awarded the 1950 Nobel Prize for Physiology or Medicine along with Philip S. Hench and Tadeus Reichstein for the discovery of adrenal cortex hormones, their structures, and their functions. Cortisone was first produced commercially by Merck & Co. On September 30, 1949, Percy Julian announced an improvement in the process of producing cortisone from bile acids. This eliminated the need to use osmium tetroxide, a rare and expensive chemical.

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Cortisone Sample Sentences in News


  • Orioles injury news: J.J. Hardy received cortisone shot for back injury on Tuesday
    O's shortstop J.J. Hardy got a cortisone shot on Tuesday and they hope he'll play again on Friday. The Orioles have been without J.J. Hardy since Friday, and it could be Friday or later before he is in a game again. Manager Buck Showalter told reporters before Tuesday's game that following that MRI, Hardy received a cortisone shot to help recover. Read more on this news related to 'Cortisone'
  • Cortisone for Hardy; Friday return the plan
    Orioles shortstop J.J. Hardy received a cortisone injection in his sacroiliac (SI) joint on Tuesday, and the plan is still for him to return to the lineup for Friday's doubleheader. Read more on this news related to 'Cortisone'
  • The right way to use cortisone injections
    On a daily basis, I am asked what the downsides of cortisone injections are.  The answer depends on location of the injection, medical history, type of steroid used, and technique. Steroid injections have received mixed reviews in the media lately, but when used judiciously, they can cure joint swelling, restore motion, and significantly reduce pain Read more on this news related to 'Cortisone'

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