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Dictionary Meaning and Definition on 'Cortisone'

Cortisone Meaning and Definition from WordNet (r) 2.0
    cortisone n : a corticosteroid hormone (trade name Cortone Acetate) normally produced by the adrenal cortex; is converted to hydrocortisone [syn: Cortone Acetate]
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Wikipedia Meaning and Definition on 'Cortisone'

220–224 °C

Cortisone (pronounced /ˈkɔrtɨsoʊn/ or /ˈkɔrtɨzoʊn/ (ˈkôrtəˌsōn or -zōn)) (17-hydroxy-11-dehydrocorticosterone) is a steroid hormone. In chemical structure, it is a corticosteroid closely related to corticosterone. It is used to treat a variety of ailments and can be administered intravenously, orally, intraarticularly, or cutaneously. Cortisone suppresses the immune system, thus reducing inflammation and attendant pain and swelling at the site of the injury. Risks exist, in particular in the long-term use of cortisone.

Cortisone was first identified by the American chemist Edward Calvin Kendall while a researcher at the Mayo Clinic. He was awarded the 1950 Nobel Prize for Physiology or Medicine along with Philip S. Hench and Tadeus Reichstein for the discovery of adrenal cortex hormones, their structures, and their functions. Cortisone was first produced commercially by Merck & Co. On September 30, 1949, Percy Julian announced an improvement in the process of producing cortisone from bile acids. This eliminated the need to use osmium tetroxide, a rare and expensive chemical.

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Cortisone Sample Sentences in News

  • Cortisone can help alleviate dogs' itches
    Skin problems, particularly itchy skin problems, can be quite frustrating to deal with, especially in summer. Read more on this news related to 'Cortisone'
  • Hanley Ramirez out of Dodgers' lineup after cortisone shot
    The Dodgers will rest Hanley Ramirez after the shortstop received a cortisone shot in his right shoulder Thursday night, Manager Don Mattingly said Friday. Ramirez is not in the starting lineup against the Padres but could be available later in the game. Read more on this news related to 'Cortisone'
  • Mark Appel gets cortisone shot in wrist
    .share-print{margin-right: 130px !important;}MINNEAPOLIS — Struggling Astros pitching prospect Mark Appel had a cortisone shot in his right (throwing) wrist about three weeks ago, agent Scott Boras said Monday. Boras said there was not a longterm concern with Appel, and said the cause was “more of a tendinitis kind of thing.” The Astros had not previously sa Read more on this news related to 'Cortisone'

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