Cortisone

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Dictionary Meaning and Definition on 'Cortisone'

Cortisone Meaning and Definition from WordNet (r) 2.0
    cortisone n : a corticosteroid hormone (trade name Cortone Acetate) normally produced by the adrenal cortex; is converted to hydrocortisone [syn: Cortone Acetate]
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Wikipedia Meaning and Definition on 'Cortisone'


220–224 °C

Cortisone (pronounced /ˈkɔrtɨsoʊn/ or /ˈkɔrtɨzoʊn/ (ˈkôrtəˌsōn or -zōn)) (17-hydroxy-11-dehydrocorticosterone) is a steroid hormone. In chemical structure, it is a corticosteroid closely related to corticosterone. It is used to treat a variety of ailments and can be administered intravenously, orally, intraarticularly, or cutaneously. Cortisone suppresses the immune system, thus reducing inflammation and attendant pain and swelling at the site of the injury. Risks exist, in particular in the long-term use of cortisone.

Cortisone was first identified by the American chemist Edward Calvin Kendall while a researcher at the Mayo Clinic. He was awarded the 1950 Nobel Prize for Physiology or Medicine along with Philip S. Hench and Tadeus Reichstein for the discovery of adrenal cortex hormones, their structures, and their functions. Cortisone was first produced commercially by Merck & Co. On September 30, 1949, Percy Julian announced an improvement in the process of producing cortisone from bile acids. This eliminated the need to use osmium tetroxide, a rare and expensive chemical.

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Cortisone Sample Sentences in News


  • Pedroia gets cortisone shot in ailing wrist
    Red Sox second baseman Dustin Pedroia said Tuesday he was given a cortisone shot to stem the inflammation in his left wrist, in an area close to where he tore the ulnar collateral ligament in his left thumb a year ago. Read more on this news related to 'Cortisone'
  • Dustin Pedroia has cortisone injection in wrist
    Red Sox second baseman Dustin Pedroia had a cortisone injection in his left wrist and hopes to return to Boston's starting lineup on Wednesday night. The AL MVP was injured April 4 when Milwaukee's Carlos Gomez broke up a double play at second base in the ninth inning. Pedroia is hitting .139 (5 for 36) since then with one RBI and no walks, leaving his sea Read more on this news related to 'Cortisone'
  • Red Sox second baseman Pedroia has cortisone shot in wrist
    CHICAGO -- Red Sox second baseman Dustin Pedroia had a cortisone injection in his left wrist and hopes to return to Boston's starting lineup on Wednesday night. Read more on this news related to 'Cortisone'

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