Cortisone

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Dictionary Meaning and Definition on 'Cortisone'

Cortisone Meaning and Definition from WordNet (r) 2.0
    cortisone n : a corticosteroid hormone (trade name Cortone Acetate) normally produced by the adrenal cortex; is converted to hydrocortisone [syn: Cortone Acetate]
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Wikipedia Meaning and Definition on 'Cortisone'


220–224 °C

Cortisone (pronounced /ˈkɔrtɨsoʊn/ or /ˈkɔrtɨzoʊn/ (ˈkôrtəˌsōn or -zōn)) (17-hydroxy-11-dehydrocorticosterone) is a steroid hormone. In chemical structure, it is a corticosteroid closely related to corticosterone. It is used to treat a variety of ailments and can be administered intravenously, orally, intraarticularly, or cutaneously. Cortisone suppresses the immune system, thus reducing inflammation and attendant pain and swelling at the site of the injury. Risks exist, in particular in the long-term use of cortisone.

Cortisone was first identified by the American chemist Edward Calvin Kendall while a researcher at the Mayo Clinic. He was awarded the 1950 Nobel Prize for Physiology or Medicine along with Philip S. Hench and Tadeus Reichstein for the discovery of adrenal cortex hormones, their structures, and their functions. Cortisone was first produced commercially by Merck & Co. On September 30, 1949, Percy Julian announced an improvement in the process of producing cortisone from bile acids. This eliminated the need to use osmium tetroxide, a rare and expensive chemical.

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Cortisone Sample Sentences in News


  • The right way to use cortisone injections
    On a daily basis, I am asked what the downsides of cortisone injections are.  The answer depends on location of the injection, medical history, type of steroid used, and technique. Steroid injections have received mixed reviews in the media lately, but when used judiciously, they can cure joint swelling, restore motion, and significantly reduce pain Read more on this news related to 'Cortisone'
  • Nats Journal: Jayson Werth receives cortisone shot to relieve AC joint sprain
    Jayson Werth will miss a few games after he received an injection to relieve pain from an AC joint sprain. Read more on this news related to 'Cortisone'
  • Dana Eveland gets cortisone shot for elbow trouble
    Mets reliever Dana Eveland got a cortisone injection for elbow trouble and is out until at least Friday's series opener with the Dodgers, reports ESPN.com. Read more on this news related to 'Cortisone'

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