Dictionary Meaning and Definition on 'Cortisone'
n : a corticosteroid hormone (trade name Cortone Acetate)
normally produced by the adrenal cortex; is converted to
hydrocortisone [syn: Cortone Acetate]
Wikipedia Meaning and Definition on 'Cortisone'
Cortisone (pronounced /ˈkɔrtɨsoʊn/ or /ˈkɔrtɨzoʊn/ (ˈkôrtəˌsōn or -zōn)) (17-hydroxy-11-dehydrocorticosterone) is a steroid hormone. In chemical structure, it is a corticosteroid closely related to corticosterone. It is used to treat a variety of ailments and can be administered intravenously, orally, intraarticularly, or cutaneously. Cortisone suppresses the immune system, thus reducing inflammation and attendant pain and swelling at the site of the injury. Risks exist, in particular in the long-term use of cortisone.
Cortisone was first identified by the American chemist Edward Calvin Kendall while a researcher at the Mayo Clinic. He was awarded the 1950 Nobel Prize for Physiology or Medicine along with Philip S. Hench and Tadeus Reichstein for the discovery of adrenal cortex hormones, their structures, and their functions. Cortisone was first produced commercially by Merck & Co. On September 30, 1949, Percy Julian announced an improvement in the process of producing cortisone from bile acids. This eliminated the need to use osmium tetroxide, a rare and expensive chemical.[See more about Cortisone at Dictionary 3.0 Encyclopedia]
Words and phrases related to 'Cortisone'
Cortisone Sample Sentences in News
- Pettibone progresses after cortisone injection
Phillies right-hander Jonathan Pettibone said he took a step forward Friday morning with his first bullpen session following a cortisone injection in his right shoulder Feb. 17. Read more on this news related to 'Cortisone'
- Report: Cardinals LHP Jaime Garcia likely out for season opener
Jaime Garcia is expected to receive a cortisone shot in his shoulder from Dr. James Andrews. (G Fiume/Getty Images) Read more on this news related to 'Cortisone'
- Phillies Notes: Phillies proceeding cautiously with Pettibone
CLEARWATER, Fla. - Rest did not heal the soreness in Jonathan Pettibone's right shoulder, so now the Phillies will inject him with cortisone. Pettibone will not throw for five days after the injection and the team hopes its 23-year-old starter can resume a normal program Saturday. Read more on this news related to 'Cortisone'